Anti-PHGDH 磷酸甘油酸脱氢酶抗体
PHGDH catalyses the first step in the serine biosynthesis pathway, and breast cancer cells with high PHGDH expression have increased serine synthesis flux.
PHGDH催化丝氨酸生物合成途径的第一步，PHGDH高表达的乳腺癌细胞丝氨酸合成通量上升。
In cells with high PHGDH expression, the serine synthesis pathway contributes approximately 50% of the total anaplerotic flux of glutamine into the TCA cycle.
在PHGDH高表达的细胞中，丝氨酸合成途径为三羧酸循环贡献了接近总量50%的谷氨酰胺回补通量。
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