The phase I study clearly showed the low toxicity of the method and the accumulation of the MMS in the target area.

i期临床研究清楚地显示，此种治疗方法是低毒性的，而且MMS能在靶区内积聚。

youdao

Yang JCH, et al. Osimertinib activity in patients (pts) with leptomeningeal (LM) disease from non-small cell lung cancer (NSCLC): updated results from BLOOM, a Phase I study.

osimertinib在非小细胞肺癌（NSCLC）所致软脑脊膜（LM）病患者（pts）中的活性：BLOOM I期研究的更新结果。

youdao

The Ad5-TRAIL gene therapy for prostate cancer research trial is a Phase I study designed to test the optimal dosage at which the therapeutic agent can safely be given to patients.

前列腺癌的Ad5-TRAIL基因疗法处于一期临床实验阶段，目的是为了得到病人安全用药的合适药物剂量。

youdao

For its part, Merck notes that its BACE inhibitor recently demonstrated a reduction in cerebral spinal fluid, or CSF, a biomarker, in a Phase I study.

FORBES: Merck Makes A 'Speculative' Step Into Alzheimer's

So why does this tiny Phase I pilot study, successful for only four of six women, matter so much?

FORBES: Startling Treatment Breakthrough For Anorexia Leads To New Understanding Of Brain Disorders

The company recently completed enrollment in a Phase I clinical study of MultiStem in heart attack patients, and is midway through a clinical study of MultiStem in leukemia and other cancer patients.

FORBES