That basal principle is to through minor 21-23 nucleotide fragments to identify complementary mRNA , urge complementary mRNA to degradate and make the relevance gene keep silence after transcription and the cell show phaenotype of definite gene deletion thereby.
其基本原理是通过是21-23个核苷酸的小片段,即siRNA特异性识别其互补mRNA,促使其降解,使相关基因处于转录后基因沉默,从而使细胞表现出特定基因缺失的表型。
参考来源 - 穿透素3在呼吸机所致肺损伤中作用机制的研究·2,447,543篇论文数据，部分数据来源于NoteExpress
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