Are there any new findings or new therapy options for treatment of PFO in recent years?

近年来是否有关于治疗PFO新的发现或新的治疗观念？

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Objective:To evaluate the feasibility of transcatheter closure of patent foramen ovale(PFO)to prevent paradoxical embolism with Amplatzer occluder device.

目的：经导管封堵卵圆孔未闭（PFO）预防脑的矛盾栓塞并评价其疗效。

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Most studies have confirmed that the incidence and recurrence of cryptogenic stroke in patients with PFO is markedly higher than in the normal population.

大量的研究结果证实伴卵圆孔未闭者发生隐性脑卒中的机率及复发率明显高于正常人群。

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She discovered she had a PFO and had the device implanted by Dr. Goldberg.

WSJ: Doctors Debate Whether Strokes Be Prevented With a Heart-Plug Procedure

The RESPECT trial similarly randomized 980 patients to medical therapy or PFO closure.

FORBES: Controversial PFO Closure Trials Published In NEJM

If approved, physicians worry the PFO closure will become another example of a well-intentioned medical procedure that will be overused.

WSJ: Doctors Debate Whether Strokes Be Prevented With a Heart-Plug Procedure