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PEDF

  • n.色素上皮衍生因子(Pigment Epithelium-Derived Factor):一种具有多种生物学功能的蛋白质,包括抗血管生成、神经保护和抗炎作用。在眼科研究中,PEDF被认为是一种潜在的治疗视网膜疾病的靶向因子。

网络释义英英释义

  色素上皮衍生因子(Pigment Epithelium Derived Factor)

...通过降解基底膜糖蛋白及细胞外基质成分,进而启动内皮细胞的激活和迁移,整合素家族通过和不同配基结合,介导血管内皮细胞的迁移和黏附,有助于新生血管的成熟和稳定,尤其是MMP2、MMP-9、MT1-MMP。 1.2抗微血管生成相关因子 色素上皮衍生因子(PEDF)是最具潜能的血管生成抑制因子,与其激活内皮细胞Fas/FasL凋亡通路有关。炎症负调控因子IL-10则能显著抑制M1型巨噬细胞释放VEGF。

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  色素上皮源性因子

色素上皮源性因子(PEDF)是一种存在于正常神经组织中的可溶性糖蛋白。它具有强大的营养和保护神经功能,对很多急慢性病变引起神经系统损伤都有很好的保护...

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短语

Anti-PEDF 色素上皮源性因子抗体

mouse PEDF 小鼠色素上皮衍生因子

Rat PEDF 大鼠色素上皮衍生因子

Human PEDF 人色素上皮衍生因子

PEDF-GFP 色素上皮衍生因子一绿色荧光蛋白

AD-PEDF 腺病毒介导的色素上皮衍生因子

PEDF Antibody 色素上皮源性因子抗体

pigment epithelium derived factor PEDF 色素上皮衍生因子

PEDF pigment epithelium-derived factor 色素上皮源性因子

 更多收起网络短语

PEDF

  • abstract: Pigment epithelium-derived factor (PEDF) also known as serpin F1 (SERPINF1), is a multifunctional secreted protein that has anti-angiogenic, anti-tumorigenic, and neurotrophic functions. Found in vertebrates, this 50 kDa protein is being researched as a therapeutic candidate for treatment of such conditions as choroidal neovascularization, heart disease, and cancer.

以上来源于: WordNet

双语例句权威例句

  • PEDF might become a valuable therapeutic agent in neurologic diseases.

    它对于神经疾病的治疗可能具有很大的潜力。

    youdao

  • Recent studies showed that PEDF had a close relationship with diabetic microangiopathy.

    近年来研究表明,PEDF与糖尿病微血管病变关系密切。

    youdao

  • Conclusion PEDF is expressed in dermal fibroblasts and is regulated by calcium and CoCl2.

    结论真皮成纤维细胞表达PEDF,而且受钙离子和氯化钴的调节。

    youdao

更多双语例句
  • Professor Ian MacDonald, an expert in the chemistry of nutrition at the University of Nottingham, said PEDF was one of many chemicals produced by fat cells and it was unclear how they all interacted with each other.

    BBC: Obesity health risk cause 'found'

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