Objective: To study the relation among cognitive dysfunction, depression and leukoaraiosis (LA) in patients with Parkinson's disease (PD).

目的：探讨帕金森病（PD）患者的认知功能障碍与抑郁和脑白质疏松症（LA）的关系。

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Methods: Study population was based on participants in routine KCIS program who were 35-44 years from 2003 to 2005. The CPI and LA were used as screening tool to assess the status of PD.

材料与方法：本研究以基隆市社区阖家欢筛检为主，邀请2003至2005年年龄35-44岁参加民众牙周病筛检，同时进行CPI及LA为筛检方法。

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