Statins increase human serum levels of PCSK9.

他汀类药物可以升高血pcsk9水平。

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"You want more LDL receptors, so blocking PCSK9 is a good thing," says Horton.

“您想要更多的低密度脂蛋白受体，使阻塞pcsk9是一件好事，说：”霍顿。

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PCSK9 binds to LDL receptors on the surface of liver cells and causes those receptors to break down.

pcsk9结合低密度脂蛋白受体表面上的肝细胞和原因，这些受体打破。

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Regeneron and Amgen, which is also developing a PCSK9 drugs, dismissed the possibility of a substantial delay.

FORBES: Analyst Is Skeptical Of Rival Company's Warnings About Regeneron

Amgen and Sanofi are interested in pursuing similar indications for their PCSK9 shots.

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It has been a hot target for drug development for several years, and PFizer and Amgen are also developing PCSK9 shots.

FORBES: New Drug Leads To Dramatic Reductions In Bad Cholesterol