The patent and Trademark Office has sided with the proponents and has issued thousands of patents on genes of various organisms, including on an estimated 20 percent of human genes.

专利及商标局一直站在支持者们那边，并且颁发了数千份关于各种生物基因的专利，包括估计20%的人类基因。

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Until 1790, each state had its own patent legislation and issued patents independently.

在 1790 年之前，各个州有自己的专利权法规，它们各自颁发专利。

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Although the Patent Office is aware of this patent being issued, the original record was destroyed along with other patents from the 18th century in an 1836 fire.

虽然专利局知道这项专利已经提交了，但原版记录在1836年的大火中同其他专利一起被烧毁了。

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Getting a patent issued can be the difference between life and death for some businesses, and start-ups especially.

FORBES: Inventors: Take Heed Of The Revised U.S. Patent Law

Patent applicants pay the PTO a fee, not a tax, to have their invention examined and, if approved, then a patent issued.

FORBES: Patent Reform and the Constitution

"By the time a patent issued, that season's designs would be out the door, and new ones would be coming in, " said Ms. Scafidi.

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