Osteoarthritis of the knees presents a particularly serious problem.

膝关节炎似乎带来了很大的问题。

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But aching bones still leave researchers perplexed. Osteoarthritis of the knees presents a particularly serious problem.

但骨痛，尤其是膝盖骨关节炎仍然让很多研究者束手无策。

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The problem is particularly serious for trading of farm produce such as pork.

这个问题对于像猪肉一样的农产品来说显得尤为严峻。

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This is a particularly serious problem because misinformation has a way of compounding itself over time.

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This is a particularly serious problem when performance results are poor.

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