But aching bones still leave researchers perplexed. Osteoarthritis of the knees presents a particularly serious problem.

但骨痛，尤其是膝盖骨关节炎仍然让很多研究者束手无策。

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This is a particularly serious problem because misinformation has a way of compounding itself over time.

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This is a particularly serious problem when performance results are poor.

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