By disturbing the body's equilibrium, anabolic steroids can potentially cause damage to many of the body's major organs, particularly the liver, which has to deal with breaking down the compound.

BBC: Nandrolone and anabolic steroids

Using such huge amounts of RNAi could be dangerous in people, and she and her colleagues picked the liver particularly because it would be easy to get the RNAi into the organ.

FORBES: Magazine Article

And it added in one case, a woman using black cohosh needed a liver transplantation after a particularly severe reaction.

BBC: Some women are using alternative therapies instead of HRT