The advisory panel decided that clinical studies presented by Transkaryotic did not provide strong evidence that the drug worked.

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Both studies helped inform an Institute of Medicine (IOM) panel that, in September 2009, issued a report recommending the use of fitted N95 respirators by health-care workers who interact with patients with confirmed or suspected cases of H1N1. (MacIntyre was also a member of that panel.) However, because the two studies were preliminary, the committee said that it could not draw conclusions from either.

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Still, the panel recommended that Glaxo do more studies that would monitor miscarriages and other problems reported by patients.

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