However, the home crowd's relief was shortlived as Ronaldo beat the offside trip to gather Mesut Ozil's fine pass down the right, and the world's most expensive player netted his 54th goal this season from an acute angle.
In the 25th minute, Reus took a quick pass from Ozil deep on the right side of the German penalty area and sent the ball across an open German goal, just beyond the outstretched leg of a sliding Klose.
Ronaldo grabbed his second and Real's fourth on 41 minutes when he again finished off a pass from Ozil and the German playmaker was the provider on the stroke of halftime as he sent Di Maria away to grab his second.