...类抗心律失常药物均为钾通道阻断剂,我们设想如果KATP通道开放剂有抗心律失常作用,那么激动钾通道就可能成为抗心律失常的新机制。此外,哇巴因(ouabain)作为一种强心苷,毒性极强,是实验室复制心律失常模型常用的工具药,但其致心律失常效应受动物种属、实验条件等因素影响较大,例如豚...
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...接着,研究者们让人类皮肤成纤维细胞在体外被暴露于不同类型的氧化应激中,这些氧化应激都增加了衰老标志物的表达、细胞损伤、细胞凋亡,并刺激了NKAL。此外,他们还用乌本苷(ouabain)进一步刺激NKAL以增强细胞衰老,而用pNaKtide治疗则减弱了细胞衰老。
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endogenous ouabain 内源性哇巴因 ; 血浆内源性哇巴因 ; 可称之为内源性哇巴因 ; 探讨内源性哇巴因
Ouabain G 毒毛旋花苷 ; 乌本苷
anti-ouabain 抗哇巴因
ouabain resistance 乌本苷抗性
ouabain-insensitive 哇巴因不敏感性
ouabain antibody 抗哇巴因抗体
ouabain injection 哇巴因注射液
ouabain resistant ouabain抵抗
N a poisonous white crystalline glycoside extracted from certain trees and used as a heart stimulant and, by some African tribes, on poison darts. Formula: C29H44O12.8H2O 乌本苷
Objective To study the relationship between the concentration of serum endogenous ouabain (EO) and glomerular diseases.
目的探讨内源性哇巴因(EO)与肾小球疾病的关系。
Furthermore, XT not only attenuated the positive inotropic action, but also delayed the following toxicity response induced by ouabain in the isolated left atria.
XT对哇巴因的正性肌力作用及随后出现的心肌收缩力降低的毒性反应均有明显的对抗作用。
Objective: To study the antiarrhythmic activity of taurine-magnesium coordination compound (TMC) in vivo by using the arrhythmic model induced by ouabain of guinea pig.
目的:建立哇巴因诱发的豚鼠心律失常模型,观察新型配合物牛磺酸镁(TMC)的在体抗心律失常作用;
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