CONCLUSION Spasmomen, Otilonium bromide is the effective medicine for IBS therapy as its less side effects.
结论斯巴敏不良反应小，是治疗IBS的一个有效的药物。
OBJECTIVE To check tradition spasmolytic and observe curative effect and safety of Spasmomen, Otilonium bromide for IBS treatment by contrast.
目的对照传统解痉剂观察斯巴敏治疗肠易激综合征(IBS)的疗效和安全性。
The stabilities of otilonium bromide in alcohols, water, acetonitrile and plasma were investigated by HPLC, and the degradation products were identified by LC-MS/MS, 1H-NMR and 13C-NMR.
试验中采用HPLC法考察奥替溴铵在醇、水、乙腈及血浆中的稳定性，并用LC-MS/MS、 1H-NMR及13C-NMR法对其降解产物进行结构鉴定。
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