奥替溴铵在不同介质中的稳定性及降解产物_stmopen 关键词】: 奥替溴铵 稳定性 降解产物 结构鉴定 [gap=1656]Keywords】: otilonium bromidestabilitydegradation productsstructural identification
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Otilonium Bromide 奥替溴铵
Otilonium Bromide Tablets 奥替溴铵片
Otilonium Br 斯巴敏 ; 奥替溴铵
Otilonium brom 奥替溴铵
Otilonium Bromi 奥替溴铵片
No degradation of otilonium was found in acetonitrile.
在乙腈中未发现降解。
The present invention discloses a medical composition comprising effective amount of otilonium Br for treating irritable bowel syndrome or stomach convulsion.
本发明公开了一种治疗肠易激综合症或胃痉挛的，含治疗有效量奥替溴铵的药物组合物。
The stabilities of otilonium bromide in alcohols, water, acetonitrile and plasma were investigated by HPLC, and the degradation products were identified by LC-MS/MS, 1H-NMR and 13C-NMR.
试验中采用HPLC法考察奥替溴铵在醇、水、乙腈及血浆中的稳定性，并用LC-MS/MS、 1H-NMR及13C-NMR法对其降解产物进行结构鉴定。
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