Osteoclastic resorption surfaces 破骨细胞吸收表面
trabecular osteoclastic resorption surface 小梁破骨细胞吸收表面
osteoclastic bone resorption 破骨细胞性骨吸收
In course of osteoclastic resorption, vacuolar proton pump in osteoclasts activated by various stimulating factors, mainly stresses, transports hydrogen ion to acidify bone matrix, forming Howship’s lacuna finally.
在骨吸收过程中,破骨细胞被各种刺激因素(主要是应力)激活后,胞内的空泡型质子泵通过转运H~+而达到骨基质的酸破坏,从而形成骨吸收陷窝。
参考来源 - 流体剪切力对体外培养的鼠破骨细胞形态和空泡质子泵mRNA的影响·2,447,543篇论文数据,部分数据来源于NoteExpress
Conclusion: Nylestriol can inhibit expression of IL 6 mRNA, reduce osteoclastic bone resorption and decrease loss of bone mass.
结论:尼尔雌醇可以抑制IL 6基因表达,从而抑制破骨细胞骨吸收,减少骨量丢失。
It is suggested that APD could directly suppress osteoclastic bone resorption and might be effective in osteoporosis.
提示APD具有较强的直接抑制破骨细胞性骨吸收的作用,对骨质疏松症可能有一定的疗效。
The effect of ICD was stronger than that of APD. Conclusion ICD directly suppresses osteoclastic bone resorption and may be effective in osteoporosis.
结论 ICD具有较强的直接抑制破骨细胞性骨吸收的作用,对骨质疏松症可能有一定的治疗作用。
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