...质细胞体外钙化能力的研究 维样基质细胞(fibroblast-like stromal cell, FSTC)是肿瘤实质成份,破骨样细胞(osteoclast-like cell, OLC)和巨噬细胞型单核基质细胞(macrophage-like stromal cell, MSTC)是其..
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变性条件下通过Ni-NTA金属螯合亲和层析对表达产物进行纯化后再经梯度透析进行复性,采用破骨细胞样细胞(osteoclast-like cell,OLC)诱导分化实验来检测重组蛋白的生物活性,证实单核/巨噬细胞集落刺激因子(M-CSF)和破骨细胞分化因子...
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摘 要 目的: 从骨吸收机制比较骨巨细胞瘤(giant cell tumour of bone, GCT) 中的破骨样细胞(osteoclast-like cell)和破骨细胞(osteoclast),明确参与破骨样细胞骨吸收的质子泵类型及其在骨吸收中的作用,进一步探讨破骨样细胞的特征和来源。
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...骨细胞诱导培养体系 GM-CSF;C组加入Dexamethasone;D组加入GM-CSF和Dexamethasone,观察各组破骨样细胞(osteoclast-like cell,OLC)及骨陷窝形成情况,并计数比较。
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c-type natriuretic peptide osteoclast-like cell c型利钠利尿肽
osteoclast-like giant cell 破骨细胞样巨细胞
Osteoclast-like giant cell tumor 破骨细胞样巨细胞瘤
The osteoclast-like cell (OLC) formation was significantly inhibited by the recombinant protein. Conclusion:The recombinant protein hOCIL was successfully obtained from E. coli with biological activity that may inhibit the osteoclast-like cell formation in vitro.
结论:本研究通过基因工程的方法成功获得了hOCIL胞外段重组蛋白,此蛋白在体外可以明显抑制破骨细胞样细胞的形成。
参考来源 - 破骨细胞抑制性凝集素胞外段可抑制骨髓干细胞向破骨细胞分化PartⅠ:The culture of osteoclast-like cell obtained from Peripheral blood mononuclear cells(PBMCs)of patients with rheumatoid arthritis in vitroObjecitive:Establish the system of osteoclast-like cell(OLC)cultural in vitro and appraise the cultured cells were osteoclasts.
第一部分类风湿关节炎患者外周血单核细胞向破骨样细胞转分化培养体系的建立目的:建立类风湿关节炎患者外周血单核细胞向破骨样细胞转分化的培养体系,并对所培养的破骨样细胞进行鉴定。
参考来源 - ~(99)Tc·2,447,543篇论文数据,部分数据来源于NoteExpress
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