floating oral delivery system 胃内漂浮片
oral delivery method 口服给药法
oral delivery system 口服给药系统
To apply oral delivery skills 难点
oral colon-specific drug delivery system 口服结肠定位给药系统 ; 给药系统 ; 口服结肠靶向释药系统 ; 释药系统
However, rotigotine has extensive first-pass metabolism,short half-time, very low oral bioavailability, making the per oral delivery route not feasible. but it has high-fat-soluble,that make it is suitable for transdermal system.
由于罗替戈汀广泛的胃肠代谢及半衰期短,生物利用度极低,不能通过口服给药产生药效,但是它的高脂溶性(油水分配系数logP=4.03)使它非常适合作成透皮贴剂。
参考来源 - 罗替戈汀离子导入经皮给药系统的研究·2,447,543篇论文数据，部分数据来源于NoteExpress
Continuous delivery of rotigotine as transdermal patches could offer similar efficacy to oral pramipexole in patients with fluctuating Parkinson's disease over 6 months of treatment.
治疗症状波动的帕金森病患者时，持续的给予罗替戈汀透皮贴片贴敷治疗（6个月以上的治疗）可达到与口服普拉克索治疗相似的疗效。
The study provided the theoretical foundation and experiment evidence for preparing oral drug delivery system of LMWH.
本课题为进一步研制LMWH口服给药系统奠定了理论基础和实验依据。
This article provides a review of starch structure, digestibility and its influencing factors and the application outlook of starch-based carrier for oral colon-specific drug delivery system.
综述了淀粉的结构、消化特性、影响淀粉消化特性的因素及其在口服结肠靶向药物控释载体中的应用前景。
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