Such a small PE such as this one would probably not be noticed or cause problems unless there were many of them showered into the pulmonary circulation at once or over a period of time.

这样的小栓子一般对机体的影响很小，只有众多的小栓子突然或者在一段时间内进入肺循环，才会造成严重影响，可能导致肺高血压。

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But a drop in oxygen levels can cause a health emergency in people with heart or lung problems.

VOA: special.2009.07.14

Local people would attack the Jews, or the Jews would try to set up an extra big meeting house for themselves, and it would cause local problems.

当地人攻击犹太人，或者犹太人企图建造超大的礼拜堂，引起各种问题。

耶鲁公开课 - 新约课程节选

They say their findings show that even low levels of smoke may cause behavior problems in children with asthma or others at risk.

VOA: special.2009.01.13

The bulk of the tumor pressing on the liver or kidney can cause problems.

CNN: What is Hodgkin lymphoma's effect on the lymphatic system?

Opponents of a minimum unit price say it is unfair because it penalises all drinkers, not just those who cause or have problems.

BBC: Minimum alcohol price in UK 'would save lives'

Fracking is under fire, as we know, from those who insist that it does or can cause huge problems to the surrounding environment.

FORBES: Ten Things to Know About Fracking