文章摘要 关键词 缺血-再灌注 电刺激 阿片肽 纳洛酮 格列苯脲[gap=915]Key words Ischemia-reperfusion Electrostimulation Opioid Naloxone Glibenclamide
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...植入性鞘内吗啡输注系统；阿片类药物；筛选试验[gap=1936]Key word] intractable pain; implanted drug delivery system; opioid; trial test ...
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Opioid Peptide 阿片肽
Opioid Receptors 阿片样物质受体
opioid peptides 阿片肽 ; 类吗啡肽 ; 阿片肽类
endogenous opioid peptide 内源性阿片肽 ; 内源性阿片肽类物质
endogenous opioid 内源性阿片类物质
Mu opioid receptor 受体 ; 阿片受体
orphan opioid receptor 孤儿阿片受体
opioid neuropeptidase 阿片肽裂解酶
Results Ith morphine enhanced the μ-opioid receptor mRNA expression in PAG and hippocampus of rats.
结果 鞘内注射吗啡可促进大鼠PAG和海马μ-阿片受体mRNA表达增加。
参考来源 - 鞘内注射吗啡抑制大鼠免疫功能时PAG和海马μNucleus accumbens plays a critical role in opioid rewarding effect and relapse.
伏核在阿片类药物奖赏作用和复吸中有重要作用。
参考来源 - 吗啡戒断大鼠伏核神经元兴奋性的改变CCK is closely linked with the reward system modulated by dopamine; acetylcholine, opioid-like substances and CCK modulate the release of dopamine and glutamate; CCK has a depressive effect on reward.
CCK与多巴胺调制的奖赏系统有着密切的联系,乙酰胆碱、阿片样物质及CCK调制谷氨酸和多巴胺的释放,CCK对奖赏具有抑制效应。
参考来源 - 慢性束缚应激大鼠行为学及NPY、CCK变化与肝主疏泄的关系These results indicate that GATl is involved in the regulation of pain processes, and point to the possibility of developing analgesic drugs that target GATl other than opioid receptors.
这些结果表明，GAT1参与疼痛传导过程的调控，并且提示可以开发新的以GAT1而非阿片样受体为靶点的镇痛药物。
参考来源 - 小鼠γ·2,447,543篇论文数据，部分数据来源于NoteExpress
以上来源于: WordNet
N any of a group of substances that resemble morphine in their physiological or pharmacological effects, esp in their pain-relieving properties 类鸦片活性肽
N of or relating to such substances 类鸦片活性肽的; 与类鸦片活性肽有关的
opioid receptor
opioid analgesic
In this review, the distribution and physiologic functions of endogenous opioid peptides in hypothalamus were discussed.
本文主要对内阿片肽在下丘脑中的分布特点及生理功能作了介绍。
The research team discovered changes in mu opioid receptors and dopamine transporters of the brain -- areas important to reward pathways.
研究团队发现在的末梢神经及大脑的多巴胺传输中，区域对酬谢路径非常重要。
Especially, some of them show biphasic modulation on opioid functions, which enhance opioid analgesia, but inhibit tolerance to and substance dependence on opioids.
特别是有些药物能对阿片功能产生双向调节作用，即增强阿片镇痛，对抗阿片耐受和躯体依赖。
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