Looking back along the way, after too much, leaving only sadness, to see only despair.

回想这一路走来，历经的太多，留下的却只有伤悲，能看到的只有绝望。

youdao

Don't let yourself despair; this will only make matters worse.

别让你自己绝望；这样将只会使情况变得更糟。

《柯林斯英汉双解大词典》

He was tortured constantly. Only when he was allowed to mingle with other prisoners again did he begin to overcome his despair.

对他的折磨从未停息，只有在被允许再次和其他犯人呆在一起的时候，他才开始克服绝望。

youdao

As for the sentiment that it is not merely the international capital market but the basic principles of capitalist economics that need to be questioned, one can only despair that the thought has even surfaced.

ECONOMIST: Heading for meltdown?

Without hope there is only despair.

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But Crusoe's journal is not only a record of despair, but an answer to it.

WSJ: Fiction as Authentic as Fact | Robinson Crusoe | Daniel Defoe | Masterpiece by Danny Heitman