Let's attack one problem at a time.

咱们一次全力处理一个问题。

《牛津词典》

It was a great trip except for one problem.

这是一次很棒的旅行，除了一个问题。

youdao

youdao

Tell us about a time when you have tried to solve one problem but unexpectedly produced another.

VOA: special.2010.05.25

We'll talk more about this later, but it often happens that when you change your program to solve one problem you break it, and things that used to work don't work.

我们以后会更多的去讨论者一点，但是经常发生的情况是当你因为,一个问题修改你的程序的时候,你修改了程序,但原来没问题的模块。

麻省理工公开课 - 计算机科学及编程导论课程节选

And one problem is that "For depression" is that there's too little of a neurotransmitter known as serotonin.

抑郁症的问题就在于,缺乏一种叫做血清素的神经递质

耶鲁公开课 - 心理学导论课程节选

There's only one problem: you can't seem to pull in a reliable OTA (over-the-air) signal.

ENGADGET: blogger-avatar

One problem: Canandaigua's acquired jug wines--Paul Masson, Inglenook and Almaden--competed for the same customers.

FORBES: Up From the Gutter

One problem, say Chen's critics, was that he didn't forewarn his top advisers of his announcement.

CNN: Did He Say 'One China'?