Rupert Isaacson has managed to discover the secret of turning one challenge into many achievements.

鲁伯特·艾萨克森成功地发现了将一项挑战转化为多项成就的秘诀。

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That's one challenge that has been put to Rawls.

这是对罗尔斯的一种挑战。

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The one challenge is creating relationships between the different objects.

这里有一个难点，就是创建不同对象间的关系。

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They had had only one splendid moment to challenge winter.

VOA: special.2009.04.11

That's one challenge and we'll talk about ways to think about engineering approaches to solve that problem.

该问题一直很具挑战性,我们会讲到,如何用生物医学工程的方法来解决它

耶鲁公开课 - 生物医学工程探索课程节选

Sometimes they challenge and contradict one another, but they are not best seen as linear, as telling a neat, linear story about Israelite religion flowering and fading.

有时候它们相互对质或矛盾，但它们从未被当作线性结构，整洁有序的故事,关于以色列宗教的兴盛与衰落。

耶鲁公开课 - 旧约导论课程节选

One challenge ahead is for ad agencies to learn how mobile location-based messaging works best.

FORBES: Mapping The U.S. In 100-Meter Squares To Target Phone Users With Very Local Offers

One challenge with embryonic stem cells, however, is preventing them from creating tumor cells.

FORBES: Magazine Article

One challenge holding back venture-backed companies outside the U.S., said Breyer, was the ability to scale.

FORBES: Superstar Venture Capitalist Jim Breyer Is Super Bullish On China