Living activities of cell require the stimulation of information objects. If one once loses the signal stimulus, cells lack the activities.

细胞生命活动需要信息物质的刺激，一旦失去信号刺激，细胞就缺乏生活力。

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Once the insured has sold his policy, he naturally loses all rights to it.

一旦受保人卖掉保险单，他自然就丧失了一切相关权利。

《柯林斯英汉双解大词典》

Once a message is sent, the SIP loses ownership of it.

一旦信息发出，SIP就完全失去了控制权。

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For a player whose game centers so much around speed, it could be a rapid decline once he loses a step.

FORBES: Marlins Going All In

Investors in those companies can tell you, once a company loses momentum it's hard to get it back.

WSJ: Writing on the Wall: Facebook May Have Known Risks, Wasn't Persuaded

And once a company loses its youthful vigour, it behoves the founder to leave, watch it suffer, then return as saviour.

ECONOMIST: Michael Dell returns to the helm of the company he founded