Anger - at the person who has died or at other people, often seemingly without cause.

对死去的亲友或其它人表现出愤怒，往往似乎没有理由。

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The cause of the disease is unknown, and it often gets better without treatment.

该疾病的成因不明，而且没有治疗时，往往会对症状有改善。

youdao

Grant makers feel anything other than giving without any financial return to an often highly specific cause is not what they want.

FORBES: Benevolent Schizophrenia - A Tale of Donors and Investors

Stroke, the third leading cause of death in the United States, often occurs without warning.

CNN: Vitamin E may reduce risk of stroke