Cutting the size of the nuclear arsenal to a small fraction of its Cold War size and focusing on terrorists rather than state-based threats may seem sensible in the present environment, but the decisions the administration is making will have consequences for decades after it leaves office.
Since 1981 we've been committed to seeking fair and verifiable arms agreements that would lower the risk of war and reduce the size of nuclear arsenals.
Israel, itself the possessor of a nuclear arsenal of unknown size, is also watching closely and is quite capable of taking unilateral action if it feels threatened as the destruction of the Iraqi reactor in 1981 showed.