Chloride channel blockers, NPPB and ATP, inhibited the currents reversibly. Moreover, the inhibition of ATP on the outward currents was stronger than that on the inward currents.
氯通道阻断剂atp和NPPB可逆性地抑制此电流，ATP的抑制作用在外向电流显著强于内向电流。
CONCLUSION: the chloride channel blockers NPPB or NFA lessen the oxidative injury of C6 cells through modulating the function of membrane and down-regulating the protein expression of CLIC4.
结论：氯通道阻断剂NPPB或NFA能够在一定程度上减轻氧化应激引起的C6细胞损伤，可能与调节细胞膜功能和下调CLIC 4蛋白表达有关。
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