Thus, it is possible to significantly suppress nonsense mutations within target genes using antisense PNAs.

由此可见，反义pna有可能在靶基因区域显著性抑制无义突变。

youdao

Duchene's muscular dystrophy and cystic fibrosis are examples of hereditary diseases that result from nonsense mutations.

无义突变能导致肌无力和囊肿纤维化等疾病。

youdao

For example, the most well-described pathway is one that recognizes nonsense mutations that result in an RNA that makes a protein that is too short.

例如最常见的一种机制识别无义突变，这会导致RNA产生过短的蛋白。

youdao

Nonsense mutations also cause 10% of cystic fibrosis cases, and the PTC drug shows promise there.

FORBES: Magazine Article

By targeting nonsense mutations in general, the PTC drug one day might help legions of patients across an expanding array of rare genetic ailments.

FORBES: Stopping the Nonsense

Nonsense mutations contribute to 1, 800 different genetic diseases.

FORBES: Stopping the Nonsense