No matter how troubled, do not forget to smile;

不论多么懊恼，不要遗忘笑容；

youdao

The couple argued fiercely and no matter how I tried to pour oil on the troubled water, they just ignored me.

那对夫妻吵架吵得很激烈，不论我如何试着平息他们的怒气，他们都不会理坐我。

youdao

No matter how I look at this issue, I cannot escape being troubled by the fact that we have in place a policy which forces young men and women to lie about who they are in order to defend their fellow citizens."

VOA: special.2010.02.06

Think twice about giving adolescents or any troubled family member unsupervised access to deadly weapons, no matter how much safety training they've had.

CNN: Guns and suicide: One mother's heartbreaking tale