No matter how hopeless it seems, never give up!

无论希望多渺茫，永不放弃。

youdao

Promise me, that you'll never give up, no matter how hopeless.

答应我，永远不要放弃，无论希望多。

youdao

"Promise me you'll survive. That you won't give up, no matter what happens, no matter how hopeless." - Titanic.

向我保证，不管发生什么，不管机会多么渺茫，你会活下来，你不会放弃。——泰坦尼克？

youdao

But no matter how tired or hopeless I am feeling, hip-hop helps me look beyond my own circumstances to find the determination I need to move forward.

NPR: Finding Hope in Hip-Hop