We construct models of reality and form new principles in order to let ourselves do what works.

为了让我们自己做有效的事，我们构建了现实的模型，形成了新的原则。

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The American is a new man, who ACTS upon new principles; he must therefore entertain new ideas, and form new opinions.

美国人是新人，办事有新原则，因此，他必须考虑新的思想，形成新的观点。

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Now that we have digitized everything, can we use new principles to organize information?

现在我们数字化了一切，我们是否能够使用新的原则来组织信息？

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And then confronted with a new case, we found ourselves reexamining those principles, revising each in the light of the other.

当我们面临新的情况时，我们重新检验这些原则，根据新的情况修正这些理由或原则。

耶鲁公开课 - 公正课程节选

That's why molecular biology, one of the reasons why it's turned out to be such a powerful tool, because if you can think creatively you can find all different ways to using these very simple principles to recombine molecules, to make unique new DNA sequences.

这就是分子生物学,如此有用的原因之一,因为如果你有创造力,你可以用各种方法,运用这些简单的原理来重组分子,创造独特的DNA新序列

耶鲁公开课 - 生物医学工程探索课程节选

Microsoft has said that its new principles are not meant to address the EU's antitrust concerns.

FORBES: Ballmer's Microsoft: Thou Shalt Not Antitrust

The new principles replace the 2008 code of practice on consultations.

BBC: Cabinet office minister Oliver Letwin

By helping them to unpack their management beliefs, to think through the new principles that organizations will need going forward, helping them to learn more systematically from these positive deviants, and most importantly, helping them design and build management experiments.

FORBES: Gary Hamel On Innovating Innovation