In order to study the attenuation of neurovirulence of SA14 14 2 attenuated vaccine virus, monkeys and mice were tested with the strain and its parent SA14 virulent strain.
为了解乙型脑炎(乙脑)减毒活疫苗弱毒株SA14 14 2神经毒力的减弱程度,本文对弱毒株及其原株SA14强毒株进行了猴体和小白鼠的致病性和病理学变化的比较试验。
Conclusion Both intracerebral and intraspinal injections were sensitive methods for neurovirulence test of OPV. The results of pathological examinations were accurate and reliable.
结论脑内注射法与脊髓内注射法均是OPV猴体神经毒力试验的敏感方法,病理结果准确可靠。
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