鼻用原位凝胶给药系统中药物吸收的影响因素与改进措施 - 中国新药杂志 关键词： 原位凝胶；鼻腔给药；药物吸收 [gap=1163]Key words： in situ gel; nasal administration; drug absorption
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nasal administration route 鼻腔给药途径
nasal administration of medicine 鼻腔给药
administration by nasal feeding 鼻饲法绐药
nasal drug administration 鼻腔局部用药
The relative bioavailability of aspirin following nasal administration was 134.4%. CONCLUSIONS It was found that the combination of aspirin with the microspheres delivery system increased the uptake of the drug across the nasal membrane.
结果：鼻腔给药的吸收半衰期长于口服给药，相对生物利用度达134.4%，结论：淀粉微球作为鼻腔给药系统，能提高药物的吸收，效果明显高于口服给药。
参考来源 - 阿司匹林淀粉微球在兔体内的药动学 Pharmacokinetics of aspirin·2,447,543篇论文数据，部分数据来源于NoteExpress
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