但由于槲皮素亲水性差、吸收差、口服生物利用度低,限制了其临床应用[1-3]。纳米混悬剂(nanosuspension,NS)是采用少量表面活性剂作为稳定剂的“纯药物”粒子所构成的一种亚微米胶体分散体系[4]。
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Nanosuspension has a lot of advantages in many routes of administration.
纳米混悬液在各种给药途径中均有优势。
The relative bioavailability of baicalein nanosuspension by oral administration were 166.1%.
以黄芩素给药做参比，黄芩素纳米混悬液给药的相对生物利用度为166.1%。
Baicalein nanosuspension by oral administration could significantly enhance the bioavailability in rats.
黄芩素纳米混悬液口服给药可显著提高生物利用度。
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