These large populations facilitate the detection of rare mutational or recombinational events.
这样的大群体有利于检出稀有的突变或重组子。
Early on, cancer cells typically flourish by disabling DNA repair and ramping up the mutational frenzy.
早前，癌症细胞往往是通过破坏DNA修复功能而快速生长，引发疯狂的突变。
Mutational activation of the BRAF oncogene is the most common genetic alteration in cutaneous melanoma.
BRAF癌基因突变的激活是皮肤黑色素瘤最常见的基因改变。
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