Methods The healthy volunteers were divided into 6 different dose groups randomly for the clinical trial including 4 single dose groups and 2 multiple dose groups.

方法采用随机分组的观察方法，共分6个剂量组，即单次和累积给药剂量组，其中单次给药剂量组4个，累积给药剂量组2个。

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Methods to analyse the difference of effects and complication of multiple dose mannitol in the treatment of 75 elderly cases with acute large area brain infarction.

方法分析不同使用方法的甘露醇对75例老年急性大面积脑梗塞的治疗效果及所致并发症的差别。

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Most prominently, teenager Jesse Gelsinger died from multiple organ failure a few days after receiving a massive dose of virus-based gene therapy in a trial at the University of Pennsylvania.

FORBES: Glaxo Brings Gene Therapy Back From The Dead

Consider, for example, the reactions of the European Medical Agency (EMA) and Health Canada to the report of the unexplained death of a U.S.-based patient less than 24 hours after receiving the first dose of Gilenya, a relatively new oral treatment for multiple sclerosis.

FORBES: The Data On Drugs' Side Effects Must Be Reliable