Objective:The linkage analysis of gene polymorphism and diseases is the common method to study the molecular biological base of multigenic diseases.

目的：基因多态和疾病的连锁分析是目前研究多基因疾病分子生物学基础的常用方法。

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The rat is a reference animal model for physiological studies and for the analysis of multigenic human diseases such as hypertension, diabetes and neurological disorders.

大鼠是研究人类疾病的理想模型动物，而利用核移植手段是创造遗传修饰大鼠的最佳手段。

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Malaria, which kills more than 1m people a year and contributes to the deaths of a further 1.7m, according to the World Health Organisation, probably falls at the multigenic end of the spectrum.

ECONOMIST: Genetics and infectious disease: The germ of an idea | The