此现象被称之为“多细胞耐药（multicellular resistance,MR）”或“群集耐药”。细胞黏附分子介导的多细胞耐药（或群集耐药）是目前细胞耐药领域研究的热点。
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Fourth,the inhibition of ILK could increase the HT29 multicellular spheroids sensitivity to drugs,suggesting it play a significant role in multicellular resistance of colon adenocarcinoma.
4、抑制ILK的表达,可以增加结肠癌HT29多细胞球的药物敏感性,提示其在肿瘤群集耐药中发挥重要作用。
参考来源 - 整合素连接激酶在结肠癌细胞群集耐药中的作用It is important to clarify the drug resistance of individual cells as well as interaction of cells. Therefore, the concept of multicellular resistance was raised.
欲克服耐药不仅要阐明个体癌细胞的耐药特性，更要考虑到细胞间的相互作用和相互协作，从而提出肿瘤多细胞耐药(MR)的观点。
参考来源 - E·2,447,543篇论文数据，部分数据来源于NoteExpress
Objective To investigate the roles of PI3K pathway in multicellular resistance of lung adenocarcinoma A549 cells.
目的探讨PI3K信号通路在肿瘤群集耐药中的作用。
Tumor, as a whole, has multicellular drug resistance ( or multicelluar-meditated resistance ).
肿瘤组织，作为一个整体，常对化疗产生耐药。
Objective To explore an optimal model of multicellular aggregates of ovarian cancer cell line A2780 and investigate the possible mechanism of ovary cancer multicellular drug resistance.
目的建立卵巢癌A2 780细胞形成的多细胞团簇模型，探讨凋亡在卵巢癌细胞群集耐药中的作用。
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