It displayed an excellent prospect in the treatment of multi-drug-resistant Gram-positive bacteria and Mycobacterium tuberculosis infection. It is expected to become another major new synthetic antibacterial agents after sulfonamides and quinolone.
这种全新的作用机制使得噁唑烷酮(oxazolidinone)类抗菌药与其他抗菌药物无交叉耐药性而备受国内外医药界关注,在治疗耐多种药物的革兰氏阳性菌和结核杆菌感染方面显示出极好的前景,有望成为继磺胺类,喹诺酮类之后又一大类新型合成抗菌药。
参考来源 - 新型抗菌药利奈唑胺及其类似物的合成初探·2,447,543篇论文数据,部分数据来源于NoteExpress
Almost half of patients with the multi-drug resistant form of the disease die.
几乎一半的病人有多种药物的耐药现象发生并导致死亡。
Substandard treatment of normal TB drives the development of multi-drug resistant strains.
对普通结核病的不规范治疗致使耐多药菌株滋生繁殖。
The clinic has seen an increase in the number of people with multi-drug-resistant tuberculosis or MDR TB.
VOA: standard.2010.07.12
He says the tuberculosis epidemic is far from over and is being aggravated by multi-drug resistant TB and its even more dangerous form, extensively drug-resistant TB.
VOA: standard.2009.12.09
"The problem with resistance means that we might be facing a situation where our currently, mostly susceptible epidemic is replaced in a decade or two by mostly multi-drug resistant disease,".
VOA: standard.2009.12.09
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