Objective to study the effect of E2F1 transcription factor on the transcriptional activity of basic transcriptional regulatory region in the ARF promoter of MTS1 gene.

目的研究MTS1基因arf启动子基础转录调控区的转录激活及其与E2 F1转录因子之间的关系。

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Conclusion: MTS1 is able to disturb the cell cycle of HO-8910 and suppress the cell division. This provides a further evidence for gene therapy of MTS1 on human ovarian cancer.

结论：MTS1基因可以改变卵巢癌细胞HO - 8910的细胞周期，这可能为卵巢癌的基因治疗提供了新的实验依据。

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