Speaking at a public meeting in the town of Carolina in South Africa's Mpumalangaprovince, Mr Motsoaledi said the large number of young girls who were HIV-positive "destroyed my soul".
Hilton Botha was removed as chief investigating officer Thursday after the prosecuting authority of Mpumalangaprovince, in early February, reinstated an attempted murder charge against him for a 2011 incident.
The Mpumalanga Parks Board, which manages state-owned reserves in Mpumalangaprovince, home to most of South Africa's wildlife, has just sold a lease to develop some of its best reserves to the Dolphin Group, a Dubai company, in a deal which also did not go out to tender and was indeed originally kept secret.