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He was not kidding. The most significant detail is the cost of his plan and its impact on our long-term budget deficit,".

VOA: standard.2009.09.12

Now, I think there's a deliberate confusion here about these lines because their precise historical significance isn't what's most significant.

这里有一个刻意而为的困惑,是关于这些句子中严谨的历史意义的,而不是关于什么是最重要的。

耶鲁公开课 - 弥尔顿课程节选

The Washington Post surveyed its readership and discovered that ask people what they thought was the most significant causes of the shooting.

华盛顿邮报》在读者中进行了调查,并且发现当询问人们,他们认为,枪杀案发生的主要原因是什么。

麻省理工公开课 - 媒体、教育、市场课程节选

However, what remains most significant about these parks is that they exist at all.

BBC: Europe��s grand old theme parks

The most significant change is that new ITINs will now expire after five years .

FORBES: In Effort to Curb Immigration Related Fraud, IRS Changes ITIN Procedures

Only then will the most significant gains of the last 100 years be truly realized.

FORBES: International Women's Day