The administration of naloxone to morphine-dependent rats to induce abstinence increased nNOS immuno-Reactivity in the hypothalamus and locus coeruleus. Conclusion: ⑴The level of serum NO raised in morphine dependent and abstinence,and that of the abstinence 3d had resumed.
结论:⑴吗啡成瘾和纳洛酮诱发戒断时大鼠血清NO浓度显著升高,而自然戒断3d后大鼠血清NO浓度基本恢复。
参考来源 - 吗啡依赖及戒断大鼠NO与nNOS的改变·2,447,543篇论文数据,部分数据来源于NoteExpress
AIM to observe the effect of melatonin (MT) on morphine withdrawal syndromes and determine the content of NO in plasma and brain tissue in morphine dependent mice.
目的观察褪黑激素(MT)对小鼠吗啡戒断反应及血浆、脑组织中NO含量的影响。
Objective: to observe the ultrastructure and synaptic number of cerebral regions related to psychological dependence in rats with different morphine dependent time.
目的:观察不同时程吗啡依赖大鼠心理依赖相关脑区超微结构和突触数量的变化。
Method: Electrical lesions of ventral pallidum were done in 12 morphine dependent rats and the drug seeking behavior was measured by conditioned place preference paradigm.
方法··:毁损依赖大鼠腹侧苍白球,利用条件性位置偏爱实验测定术前、术后依赖大鼠对注射吗啡侧的偏爱程度,评价腹侧苍白球在药物强化效应程度中的作用。
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