Objective To investigate the changes in CREB-1 protein expression in three brain regions induced by acute or chronic morphine dependence and withdrawal.
目的研究急性或慢性吗啡依赖和戒断大鼠脑组织环腺苷酸反应元件结合蛋白-1 （CREB-1）表达的变化。
ObjectiveTo investigate the effect of NMDA receptor antagonist MK801 on the negative affection induced by withdrawal from acute morphine dependence in rats.
目的谷氨酸NMDA受体拮抗剂地卓西平（MK801）对大鼠急性吗啡依赖戒断性情绪反应的影响。
In addition, the withdrawal symptoms precipitated by naloxone in morphine dependent rats were blocked by methoctramine(ip) or pirenzepine (it) at single dose injection in a dose dependent manner.
美索四氨或哌拉唑嗪以剂量依赖方式抑制吗啡依赖大鼠纳洛酮激发的戒断症状。
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