There is no mistake about it; there are hard things in life.

这句话说得不错，生活中确实有许多艰难的事。

youdao

Make no mistake about it: you’ll work hard, or you won’t succeed.

毫无疑问的是：你必须努力工作，否则你不会成功。

youdao

Make no mistake about it: Internet hosting is a competitive business.

请不要误解：Internet 托管是个极具竞争性的业务，有很多选择。

youdao

When a friend is troubled by a mistake he has made, you might tell him to forget about it.

VOA: special.2009.05.10

People make mistakes and it is very possible to make a mistake about your own interests.

人们都会犯错,而更可能的,是误判其自身的利益。

耶鲁公开课 - 政治哲学导论课程节选

So I think this question is very much related to your first one about how we mistake what success really means.

我觉得这个问题与,你的第一个问题紧密相连,就是“我们对于成功的错误理解“

普林斯顿公开课 - 人性课程节选

"Make no mistake about it, they are really struggling, " said the former Scotland striker.

BBC: Ally McCoist hails Madjid Bougherra's World Cup display

But make no mistake about it: More mergers will be hitting the biotech sector soon.

FORBES: For Drug Deals, Think Small

Make no mistake about it Apple has some serious consumer insight tools and analytics.

FORBES: Apple's Bet: Threats Are Opportunities