The enzyme's chief duty is to support the pathway that ensures that cells remain healthy and clutter free by breaking down proteins that are misfolded or have outlived their usefulness.

这种酶的主要功能是支持确保细胞健康的通路，并降解清理那些错误折叠的或已经完成使命的蛋白质。

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Endoplasmic reticulum (ER) stress results from the accumulation of unfolded or misfolded proteins in the ER.

内质网应激是内质网内未折叠或错误折叠蛋白积聚所致。

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One of its main actions is to recognize misfolded or unfolded proteins and then correct the misfolding or unfolding.

其主要作用之一就是识别错误折叠或未折叠蛋白质，并继而纠正这种错误折叠或未折叠。

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It is vitally important, because misfolded proteins either do not work at all or do things that they shouldn't.

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According to the prion hypothesis, however, they are caused by misfolded proteins.

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The odd thing about prion diseases is that the misfolded protein in question somehow acts as a catalyst for other protein molecules of the same type to misfold in the same way.

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