Endoplasmic reticulum (ER) stress results from the accumulation of unfolded or misfolded proteins in the ER.

内质网应激是内质网内未折叠或错误折叠蛋白积聚所致。

youdao

One of its main actions is to recognize misfolded or unfolded proteins and then correct the misfolding or unfolding.

其主要作用之一就是识别错误折叠或未折叠蛋白质，并继而纠正这种错误折叠或未折叠。

youdao

And chemicals that seem either to prevent the misfolding, or to help the body clear away misfolded molecules, do, indeed, exist.

能阻止分子错误折叠或帮助机体清除错误折叠分子的化学药品似乎确实存在。

youdao

It is vitally important, because misfolded proteins either do not work at all or do things that they shouldn't.

ECONOMIST: What video-game technology can do in the real world

According to the prion hypothesis, however, they are caused by misfolded proteins.

ECONOMIST: Creutzfeldt-Jakob disease

The odd thing about prion diseases is that the misfolded protein in question somehow acts as a catalyst for other protein molecules of the same type to misfold in the same way.

ECONOMIST: Creutzfeldt-Jakob disease