In the pathological process of AD,microglial cells and astrocytes are activated to produce a product of a series of immune responses. Tumor necrosis factor-α(TNF-α),IL-1β(IL-1β) have high expression.
在AD的病理过程中,小胶质细胞和星形胶质细胞被激活,产生一系列免疫反应产物,其中肿瘤坏死因子-α(TNF-α)和白介素-1β(IL-1β)是胶质细胞产生的主要细胞因子。
参考来源 - 构建稳定表达炎症因子TNFα、IL·2,447,543篇论文数据,部分数据来源于NoteExpress
This is an example of neuronophagia in which a dying neuron is surrounded by microglial cells.
噬神经细胞现象,这个垂死的神经元被周围小胶质细胞包围。
A close temporal and spatial relationship between migration of microglial cells toward the photoreceptor cell layer and progression of photoreceptor degeneration was noted.
小胶质细胞向感光细胞层的迁移与感光细胞凋亡之间存在紧密的时间和空间关系。
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