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The 3,4,5 trimethoxybenzaldehyde is synthesized from p cresol in four steps of bromination, hydrolyzation, methoxylation, and methylation, with an overall yield of 53.
以对甲酚为原料经溴化、水解、甲氧基化和甲基化4步反应合成药物中间体3，4，5-三甲氧基苯甲醛，总收率达53。
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