The linear calibration curves were obtained in the concentration range of 5.0-4000 ng/mL for methacycline and 5.0-8000 ng/mL for doxycycline. The method has a lower limit of quantification (LLOQ) of 5.0 ng/mL for both methacycline and doxycycline.
美他环素的线性范围为5.0~4000ng/mL,多西环素的线性范围为5.0~8000ng/mL,定量浓度下限均为5.0ng/mL。
参考来源 - 液相色谱—串联质谱法定量分析血浆中四种抗生素药物研究·2,447,543篇论文数据,部分数据来源于NoteExpress
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