The compound (5) was got in the yield of 95% by this method. The best mole rate of Lewis acid and compound (4) andKBHt, was 1:0.25:2, The best temperature is 90@ within 10h. The best volume of MeOH is compound (4) (weight) :MeOH (volume) =1:6.
最佳反应条件为化合物(4):Lewis aeid:硼氢化钾(mol)二1:0.25:2;甲醇:化合物(4)(体积:重量比)=6:l;反应温度:90℃;反应时间:10h。
参考来源 - 甲磺酸达氟沙星的合成新工艺研究·2,447,543篇论文数据，部分数据来源于NoteExpress
以甲醇为提取溶剂；
Methods Gimeracil polymorphs were prepared by alkali-acid treatment or recrystallization with EtOH, MeOH, etc.
方法分别以“碱溶-酸析”法或甲醇、 乙醇等有机溶剂重结晶法，制备吉美拉西的多晶型。
We have determined the content of bergenin in the rhizome and MeOH extractive of Rodgersia aesculifolia Batal by TLC-scanning method.
采用薄层扫描法测定了鬼灯檠根茎、醇提物中岩白菜素的含量。
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